These include NT5E (CD73) and ENTPD1 (CD39) which are involved in immunosuppressive adenosine signaling [51], LGALS1 (galectin-1) and TGFB1, which encode for anti-inflammatory cytokines [52,53], and CD274 (PD-L1), which binds to PD-1 to initiate an inhibitory signaling pathway in anti-tumor immune cells [54]. The gene discussed is ENTPD1; the disease is neoplasm.