In turn, in the case of lung adenocarcinoma, a set of 10 genes and their genetic variants associated with chemotherapy resistance has been identified (namely, PLEK2, TFAP2A, KIF20A, S100P, GDF15, HSPB8, SASH1, WASF3, LAMA3 and TCN1). The gene discussed is HSPB8; the disease is lung adenocarcinoma.