PLEK2 and lung adenocarcinoma: In turn, in the case of lung adenocarcinoma, a set of 10 genes and their genetic variants associated with chemotherapy resistance has been identified (namely, PLEK2, TFAP2A, KIF20A, S100P, GDF15, HSPB8, SASH1, WASF3, LAMA3 and TCN1).