YWHAQ and colorectal cancer: Indeed, members of the 14-3-3 protein family have been shown to be upregulated in several types of cancer and to promote cancer progression, which is the case, e.g., for 14-3-3γ in colorectal cancer [73] or 14-3-3ζ in non-small cell lung carcinoma [74] and hepatocellular carcinoma [75].