TP53 and neoplasm: The same result is achieved as RSV interferes with inhibiting the STAT3 signaling pathway, which regulates a variety of tumor-promoting gene promoters, such as VEGF, c-MYC, cyclin D1, and survivin, and induces the S phase cell cycle arrest by activating the silent transformation regulator 1-tumor protein p53 (Sirt1-p53) pathway involved in the nuclear translocation of Sirt1 and p53.