FAS and B-cell chronic lymphocytic leukemia: In a study by our group in patients with chronic lymphocytic leukemia, 20 mL of olive oil rich in oleocanthal and oleacein increased caspase-cleaved cytokeratin-18 (ccK18) and apoptosis antigen 1 (Apo1)-Fas, were implicated in apoptosis and decreased survivin and cyclin D [156].