After the tumor was established in the mouse model and surgically resected, different treatment methods were applied to different groups, including tumor resection only, tumor resection followed by the implantation of the BP@HA-DA-Plu hydrogel, tumor resection followed by the implantation of the BP-Ag@HA-DA-Plu hydrogel (Figure 9B), and the implantable BP-Ag@HA-DA-Plu hydrogel combined with near-infrared (NIR) light irradiation after tumor resection. The gene discussed is RENBP; the disease is neoplasm.