Similarly, breast cancer (BC) diagnosis has benefited from research on exosomal proteins, including heat shock protein 70 (HSP70), thrombospondin-1 (TSP1), lactate dehydrogenase C4 (LDH-C4), exo-Anx2, and integrin α6, all of which show diagnostic potential and contribute to disease monitoring [98]. Here, THBS1 is linked to breast cancer.