After further adjustment for SBP, DBP, duration of diabetes, ALT, Cr, UA, OC, β-CTX, PINP and 25(OH)D compared with Q1 of the AST/ALT level, subjects in Q3 and Q4 remained considerably more likely to have osteopenia/osteoporosis (Q3, OR 3.478, 95% CI 1.641–7.411; Q4, OR 15.278, 95% CI 6.377–36.837) (Table 4). This evidence concerns the gene GPT and osteoporosis.