In our study, we observed that semen samples collected in the third month post‐COVID‐19 showed relatively lower levels of cytokines, including IL‐1β, IL‐6, IL‐7, IL‐8, IL‐9, IL‐15, G‐CSF, GM‐CSF, IFN‐γ, TNF‐α, PDGF, IP‐10, MIP‐1α, MIP‐1β, and MCP‐1, compared with those in samples in the first month. The gene discussed is IL1B; the disease is COVID-19.