Beyond that, the results of TIDE algorithms showed that CD248 expression was positively correlated with CAFs infiltration in various cancers, including BLCA (Rho = 0.79), BRCA (Rho = 0.629), COAD (Rho = 0.811), HNSC (Rho = 0.753), KIRC (Rho = 0.623), KIRP (Rho = 0.526), LGG (Rho = 0.481), LIHC (Rho = 0.662), LUSC (Rho = 0.794), STAD (Rho = 0.73) (Figures 5B–K), GBM (Rho = 0.584), HNSC (HPV-) (Rho = 0.726), HNSC (HPV+) (Rho = 0.806), OV (Rho = 0.679), PAAD (Rho = 0.818), and THYM (Rho = 0.287) (Supplementary Figures S2A–F) (P < 0.001). The gene discussed is CD248; the disease is cancer.