ANGPTL8 and metabolic dysfunction-associated steatotic liver disease: Therefore, the present systematic review aimed to synthesise the existing relevant studies and meta-analyze the available data on the differences in circulating levels of ANGPTL8 between patients with NAFLD or MAFLD or MASLD and controls in order to investigate its potential utility as a serum biomarker for the diagnosis and monitoring of steatosis/steatohepatitis.