PF4 and anti-neutrophil cytoplasmic antibody-associated vasculitis: Given the potential link between excessive NET formation and the development of anti-PF4-mediated immunothrombosis (16, 17), we quantified NETosis markers at five critical time points: at the diagnosis of ANCA-associated vasculitis, during the acute phase of anti-PF4-mediated immunothrombosis, and at three intervals following recovery.