Moreover, pathway analysis identified different inflammation cell signaling processes likePHONG_TNF_RESPONSE_NOT_VIA_P38, ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP and ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP (i.e. TNFRSF10B, SMAD3, TNIP2, DSE, B4GALT5 and NFKB) and cancer processes like KEGG_PATHWAYS_IN_CANCER including AML and lymphoma (i.e. SMAD3, JAK1, PIK3R5, NFKB1, SLA) (Supplementary Table 6). This evidence concerns the gene SMAD3 and cancer.