Future studies on SIC can consider including these psychosocial factors in the research category, comprehensively evaluate their interaction with biological factors, develop more comprehensive and effective treatment and management programs, and promote the overall recovery of patients.DVL1 expression is upregulated in a variety of cancers (such as colorectal and gastric cancers) and is closely associated with the abnormal activation of the Wnt signaling pathway. Here, DVL1 is linked to cancer.