Future studies should also cover a wider range of cell types and explore in-depth the function of DVL1 in different microenvironments (e.g., tumor microenvironment and immune system).At the same time, the development of “off-the-shelf” gene therapy nanoparticles based on existing drugs or the use of CRISPR technology also provides new possibilities for clinical applications in medicine (147, 148). This evidence concerns the gene DVL1 and neoplasm.