VEGFA and cancer: In health and disease, VEGF is expressed on the surface of many different cell types, including monocytes, endothelial cells, lymphocytes, and granulocytes,1, 11but it is thought that VEGF levels in these cells are higher in cancer than in healthy individuals.12Platelets, cells that are essential for thrombosis, are also rich in VEGF, which is stored within their alpha granules.1In cancer, both radiotherapy and chemotherapy have been shown to increase VEGF within tumours.13