VEGF is also found in higher levels in patients with cancer compared to healthy controls,1due to ongoing angiogenesis required for tumour growth and survival.1Interestingly Musolino et al21showed that in patients with myeloproliferative neoplasms increased plasma VEGF levels were seen up to 1 month post thrombotic event, possibly indicating a state of platelet hyperactivation and/or indicating a more global contribution of VEGF to thrombosis. This evidence concerns the gene VEGFA and myeloproliferative disorder.