Interestingly, many of the genes linked to the differentially methylated CpGs have been associated with liver disease progression (eg, DCP2, TRPV3, ARRB1, KCNIP4, MIR10A) and cancer formation or progression (eg, MTHFR, GRIK2, GSN, HOX3, KCNMA1) (Table 2). Here, ARRB1 is linked to liver disorder.