TSPO and Alzheimer disease: Using positron emission tomography, brain TSPO signals have been found to significantly correlate with age, AD pathology, and cognitive deficits (Dani et al. 2018; Edison et al. 2008; Fan et al. 2015; Finze et al. 2023; Hamelin et al. 2016; Kreisl et al. 2013; Parbo et al. 2017; Pascoal et al. 2021; Versijpt et al. 2003).