The promoter methylation levels of CCT5 were downregulated in BLCA, BRCA, CESC, CHOL, COAD, ESCA, HNSC, KIRP, KIRC, LIHC, LUAD, LUSC, PAAD, PRAD, READ, SARC, TGCT, THCA, and UCEC and were comparable between tumor and normal tissues (p < 0.05). The gene discussed is CCT5; the disease is bladder transitional cell carcinoma.