CD4 and neoplasm: In most tumor samples across the 33 types of tumors, CCT5 was positively correlated with Macrophages M0, Macrophages M1, Macrophages M2, resting memory CD4 T cells in most tumors, while was negatively associated with T cell regulatory Tregs, activated NK cells, Plasma cells, memory B cells, and CD8 T cells (Supplementary Fig. 4E).