To further validate these findings, we performed immunohistochemical staining for YOD1 and ZNF24 in a tumor microarray for ccRCC (cohort 1) (Fig. 8E), which consisted of 80 paired tumor and normal tissue samples and an additional 110 surgical tumor samples (cohort 2) (Fig. 8F). Here, YOD1 is linked to nonpapillary renal cell carcinoma.