Parkinsonism has been described in patients with IgLON5- [25], LGI1- [10,26], Ma2- [27] and Ri-Abs [28], while chorea can be present in AE associated with several autoantibodies targeting both cell surface and intracellular antigens, as illustrated in Table 1 and Fig. 1. The gene discussed is LGI1; the disease is Parkinson disease.