TET2 and pulmonary arterial hypertension: Importantly, our published hemodynamic data from these patients showed that PAH associated with a TET2 mutation is not hemodynamically more severe than idiopathic PAH; however, no subject with a TET2 mutation was responsive to acute vasodilator challenge (vs. 13.2% responders in the balance of the PAH biobank cohort) (Potus et al. 2020).