The Royal Devon University Healthcare (RDUH) NHS Foundation Trust (formerly Royal Devon and Exeter NHS Trust) and University of Exeter Medical School (UEMS) created a simple prediction rule, described in Table 7, deriving four from an original 186 variables (CRP, serum albumin, respiratory rate, WCC) to identify CDI patients' 30-day mortality risk. The gene discussed is CRP; the disease is clostridium difficile infection.