GSTM1 and ischemic stroke: Nevertheless, supplementation with the KG diet effectively reduces infarct size and edema, improving functional outcomes and providing neuroprotective effects against ischemic stroke, as shown in Fig. 3B and C. To examine the effects of the KG diet on hemorrhage, brain tissue Hb content was estimated as an index for the incidence of intracerebral hemorrhage in perfused brains at 72 h after pMCAO (Fig. 3D).