ETS-harboring TERT duplications were first reported in PTC and PDC [7] and shortly after in glioblastomas [45] and other tumors (glioblastoma multiforme, bladder urothelial carcinoma, hepatocellular carcinoma, squamous cell carcinoma of the oropharynx, duodenal adenocarcinoma, and malignant phyllodes breast tumor) [46]. The gene discussed is TERT; the disease is hepatocellular carcinoma.