CRP and cancer: The cause of this increase is the transient bacteremia and the extent of surgical trauma.19 Graziani et al. demonstrated that this can be avoided using less intensive periodontal treatment approaches, such as quadrant-based therapy.20 In our study, the average time from non-surgical periodontal treatment to the surgical procedure was 40.3 days, which, according to research, should not impact the increase in CRP levels after the cancer resection surgery.