MAPT and Alzheimer disease: Protein aggregates are common pathological findings in several neurodegenerative diseases, including intracytoplasmic Lewy bodies composed of alpha-synuclein (α-SYN) in Parkinson’s disease (PD) [1], extracellular amyloid β (Aβ) consisting of senile plaques, and intracytoplasmic tau in Alzheimer’s disease (AD) [2].