In colorectal cancer, FMRP appears to control resistance to programmed cell death, specifically necroptosis, by regulating receptor-interacting protein kinase 1 (RIPK1) mRNA and protein expression, providing insights into the mechanisms underlying cell death resistance in colorectal cancer and suggesting FMRP as a potential therapeutic target for overcoming this resistance.203. This evidence concerns the gene RIPK1 and colorectal cancer.