The lncRNA TMEM44-AS1, for instance, can inhibit ferroptosis and stabilize GPX4 mRNA, thus promoting the malignant growth of esophageal squamous cell carcinoma (ESCC) by binding to the RNA-binding protein IGF2BP2 (Yang R. et al., 2023). The gene discussed is IGF2BP2; the disease is esophageal squamous cell carcinoma.