FADS1 and Alzheimer disease: Baicalin improves cognitive function by regulating immunoglobulin-related protein expression and FADS1 succinylation modification, while Isoimperatorin exerts neuroprotective effects by simultaneously inhibiting neuroinflammation and oxidative stress (Zhao et al., 2024), Furthermore, folic acid supplementation has been reported to have beneficial effects on AD symptoms (Chen et al., 2021).