The synthetic vitamin K3 thio-derivative (VKT-1) inhibited tumour cell lines overexpressing ABC transporters (P-GP, ABCB5, BCRP) by causing cell arrest, inducing apoptosis, blocking migration and degrading microtubules in U2OS-GFP-α-tubulin cells [174]. This evidence concerns the gene ABCG2 and neoplasm.