Therefore, we cultured psoriasis T cells with MDDCs (26, 27, 43), as typical alloantigen-presenting cells, in the presence of high (1,000 U/mL) or low (300 U/mL) human recombinant (hr) IFN-α concentration, administered at the time of the first alloantigen encounter (Figure 9a). This evidence concerns the gene IFNA2 and psoriasis.