INO80E is in a gene-dense region of chromosome 16 (16p11.2) containing multiple genes that have evidence of association with schizophrenia (Ikeda et al. 2019), but has historically been of particular interest to researchers in the context of schizophrenia because of its role in DNA damage repair and neurotransmitter release (Poli et al. 2017). The gene discussed is INO80E; the disease is schizophrenia.