JUN and acute kidney injury: Jun and Junb, members of the activator protein 1 (AP-1) transcription factor family, were upregulated in the sequencing data of TCMK-1 cells treated with S100A8/A9hi M1-type RAW264.7 culture supernatants, as well as in AKI mouse models and patients, consistent with previous reports (Liu et al., 2017; Gerhardt et al., 2021).