The BA children leukocytes had higher expression of MMP-9 (p < 0.0001), TIMP-1 (p=0.028), TIMP-2 (p=0.007), IL-6 (p=0.016), and TGF-β (p=0.023) than the leukocytes of the control group. Here, TIMP1 is linked to breast angiosarcoma.