Near-infrared fluorescence (NIRF) imaging techniques using tumour-targeting tracers, such as 111In-labelled dodecane tetra-acetic acid (DOTA)–labetuzumab-IRDye800CW15, a carcinoembryonic antigen (CEA)-specific tumour-targeted dual-labelled agent, may aid in the intraoperative identification of malignant tissue of colorectal origin16–18. The gene discussed is CEACAM5; the disease is neoplasm.