Next, receiver operating characteristic (ROC) curves were generated based on the expression levels of PBX2, PRMT1, SMARCC1, and IGF2BP2 in the 85 HNSCC samples, yielding area under the curve (AUC) values of 0.853, 0.896, 0.864, and 0.893, respectively (Figure 7J). This evidence concerns the gene SMARCC1 and head and neck squamous cell carcinoma.