CRP and acute myocardial infarction: For example, C‐reaction protein (CRP), an inflammatory marker, is associated with plaque instability and rupture,[26] while cardiac troponin (cTn) is essential for diagnosing acute myocardial infarction as it indicates myocardial necrosis.[20] However, self‐quenching and leaching are common issues in these small molecular biosensors which can affect accuracy and sensitivity, thus limiting the development of this technique to a certain extent.