G6PD and malaria: Although it is currently unclear whether P. cynomolgi relapse occurs in humans, the potential occurrence of hypnozoites is of clinical significance as the treatment for relapsing malaria such as P. vivax requires using 8-aminoquinolines drugs (e.g. primaquine), which have a hemolytic effect on glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals [30].