2.5.2 Univariate cox regression analysis of the influencing factors of overall patient recurrence suggested that multifocal, LNM, ETE, higher recurrence risk stage, higher TSH, positive RET rearrangement, and RET rearrangement interacting with Hashimoto's effect were the correlates of postoperative recurrence after PTC (P < 0.05), whereas gender, age, tumor diameter, simple combined Hashimoto's, positive BRAF mutation, BRAF-interacting RET and BRAF-interacting bridging effects were not related to them (P > 0.05). The gene discussed is BRAF; the disease is neoplasm.