To understand how this pattern looks across AML patient sample Set B (3 healthy and 6 AML bone marrow aspirates), we first looked at all CD45+ cells, where 34-54% of healthy and 14-61% of AMLs were mAb2+, with the reference OCI-AML3 as 100% positive (Figure 5G). Here, RUNX2 is linked to acute myeloid leukemia.