SRSF3 and bladder transitional cell carcinoma: qRT-PCR and western blot analysis demonstrated that SRSF3 knockdown or Ser108 mutation also reduced ULK1 mRNA and protein levels (Fig. 7H and Supplementary Fig. S8B), consistent with the correlation between SRSF3 and ULK1 mRNA expression observed in the TCGA BLCA dataset (Supplementary Fig. S8C).