In vivo quantification of Tet2-mutant versus wild-type myeloid cell subsets revealed that Tet2-mutant CD11b+ monocyte-derived macrophages preferentially accumulated in the tumor relative to adjacent normal lung (Fig S27H), an effect that was not observed for their monocyte precursors or neutrophils (Fig S27H–I). Here, TET2 is linked to neoplasm.