IL1RAPL2 and psychiatric disorder: To this end, we integrated the transcriptomes of mPFC neuron subtypes (26, 27) with the genome-wide association study (GWAS) datasets of various psychiatric diseases and identified an mPFC layer 5 (L5) neuron subtype that expresses interleukin-1 receptor accessory protein-like 2 (Il1rapl2), which is highly associated with social deficit disorders.