WDR5 and synovial sarcoma: To testify the involvement of WDR5 for SS growth, we introduced either one of the two WDR5-specific short hairpin RNAs (shRNAs) to a panel of human SS cell lines carrying SS18::SSX (HSSY-II, SYO-1, Yamato-SS, and MoJo) to induce knockdown (KD) of WDR5 (fig.