RPS6KB1 and cytomegalovirus infection: With T389 phosphorylation-specific antibody, we found that S6K T389 phosphorylation was significantly elevated upon HCMV infection, while no observable changes were detected in UV-HCMV-infected and non-infected control cells consistent with the previous report on HCMV infection-induced mTOR activation (Fig 3A) [22].