PLCE1 and cancer: Accumulating evidence has shown that PLCE1 promotes cell growth, migration, and metastasis in multiple human cancers, including hepatocellular carcinoma, non-small-cell lung cancer, head and neck cancer, bladder cancer, gastric cancer, and prostate cancer (Abnet et al., 2010; Fan et al., 2019; Liao et al., 2017; Ma et al., 2011; Ou et al., 2010; Wang et al., 2020; Yue et al., 2019).