To further investigate the protective effects of these epitope peptides as influenza vaccine candidate peptides, 10 peptides were selected each from the verified HLA-A*02:01- and HLA-A*11:01-restricted epitope peptides (Figure 4A,B) for immunization in the HLA-A2/DR1 transgenic and HLA-A11/DR1 mice. The gene discussed is HLA-A; the disease is influenza.