Additionally, 15 patients reported a ≥1.5-fold increase in only one cytokine in the post-BD samples (IL-2R: 5 pts, IL-6: 3 pts; TNF-α: 2 pts, IL-10: 7 pts); also, in these cases, we did not evidence abnormal reactogenicity. The gene discussed is IL2RA; the disease is Behcet disease.