Conversely, anti-ACE2 could be investigated to determine potential biological effects, which would be particularly relevant given the heterologous human population, by which factors like age, sex, and obesity have a notable impact on the expression of ACE2 [34,35,36]—a dose–response of anti-ACE2 could be revealing. This evidence concerns the gene ACE2 and obesity due to melanocortin 4 receptor deficiency.