ITGA3 and neoplasm: Notably, integrin subunit alpha 3 (ITGA3) and ITGA6 showed significantly increased expression in patients with HNSCC, with higher levels of ITGA3 linked to poorer overall and relapse-free survival rates.(38) We observed the downregulation of miR-150-5p and upregulation of ITGA6 in tumor tissues, consistent with the findings of Koshizuka et al.(38) This interaction was predicted only by miRWalk.