In contrast, the dermis of both AD and healthy skin showed overall weak NAV1 staining, similar to that observed with control IgG staining (Figure 6E, Dermis: HC 15 ± 3.2 vs. ad 16 ± 3.2 vs. Control IgG 14 ± 2.5, p = 1.0 in HC vs. AD, p = 0.71 in HC vs. Control IgG). The gene discussed is NAV1; the disease is Alzheimer disease.